耳垂上的摺痕 ≈≈ 冠狀動脈粥樣硬化性心臟病 / 缺血性心臟病

上述標題，是一個古老的發現。古老到44年前的1973年，Dr. Sanders T. Frank在權威的《新英格蘭醫學》學術刊物上，首次以公開信的形式提出這一發現。

How Could Ear Creases Indicate Heart Disease?

Scientists aren’t sure how these two might be connected, but there are some theories. Degeneration of the elastic tissue around the small blood vessels that carry blood to the earlobes produces the earlobe crease. This is the same type of change in blood vessels associated with CAD. In other words, visible changes that show up in tiny blood vessels of the ear could indicate similar changes in those blood vessels that can’t be seen around the heart.

Rare disorders like Beckwith-Wiedemann syndrome, an overgrowth disorder, in children or genetic factors such as race and earlobe shape also can cause a crease. So how concerned should you be if you have an earlobe crease?

Supporting Studies

Several scientists have looked at the potential connection between earlobe creases and CAD. Some studies have shown a correlation, while others have not.

A study of 340 patients published in 1982 found an earlobe crease to be a sign associated with aging and CAD. The crease suggested the presence of a more severe form of heart disease in people who were showing symptoms. The earlobe crease, the researchers wrote, “may identify a subset of patients prone to early aging and to the early development of coronary artery disease, whose prognosis might be improved by early preventative measures.”

Another study published in 1989 studied the bodies of 300 patients who had died from various causes. In this study, the diagonal creases were associated with cardiovascular causes of death. The researchers wrote, “We found a strong association between earlobe creases and a cardiovascular cause of death in men and women after age, height, and diabetes had been controlled for.”

A 1991 study found similar results. So did a study publsihed in 2006, which reported that an ear crease in people younger than age 40 was a sign of CAD in up to 80 percent of cases. In a 2012 study, 430 patients with no history of CAD were examined for ear creases and then given a CT scan for CAD. Those with an ear crease were more likely to have CAD.

Contrary Findings

Other studies have shown different results. A study in 1980 showed no significant relationship between ELC and CAD in American Indians. This indicates that “Frank’s sign” may not show the same correlation in other ethnic groups. Another study of Japanese Americans living in Hawaii also found no connection. Studies have indicated that the sign may be less indicative in people who have other important risk factors for CAD, particularly diabetes.

Some studies have theorized that as people age, the presence of earlobe creases and heart disease increase — especially after they reach age 50. This doesn’t necessarily mean that one has to do with the other. A study by University of Massachusetts Medical School concluded that earlobe creases are a simple feature of the aging process in some people.

http://www.healthline.com/health/heart-disease/ear-creases#Opposition4

2014年4月，五位中國學者發表的學術論文稱，在449名耳垂有摺痕的中國人當中，46.2%沒有冠心病，但卻有更高的血管狹窄的可能性；所有冠心病患者中，75.2%有耳垂摺痕。

This cohort study investigated 449 consecutive Chinese, 250 cases with CAD and 199 without CAD, who were certified by coronary artery angiography in our center. Characteristic differences and the relation of DELC to CAD were assessed by Chi-square and t tests. The multivariate regression was performed to adjust for confounders and ROCs mode were used to detect its predicting performance for CAD.

Results

The prevalence of DELC was 46.2% in those without CAD and 75.2% in those with CAD (P < .001). Subjects with DELC had more stenostic vessels and higher prevalence of both any and significant coronary artery stenosis than those without DELC (P < .001). 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994203/

Steven Spielberg with left DELC (red arrow). Photograph: Gabriel Bouys/AFP/Getty Images

Why A Creased Earlobe May Kill You And Other Hidden Signs Of Heart Problems

http://bottomlineinc.com/why-a-creased-earlobe-may-kill-you-and-other-hidden-signs-of-heart-problems/

     心臟好不好，看耳垂，有這種耳垂症狀最危險！

                2016-10-18 in 健康

身體的外在變化往往是內在疾病的潛在徵兆，醫學界不斷嘗試驗證這些徵兆與病症的關聯性，所得出的相關性結果也令人訝異。其中一項關於「耳垂」超過三十年的研究可能指出：耳垂上出現對角線摺痕，可能是冠狀動脈阻塞等心血館疾病的徵兆！

耳垂異常折線是「血管末端阻塞」的徵兆

Sanford Frank醫生在1973年發表於新英格蘭醫學雜誌的投稿指出，耳垂上出現摺痕與心臟疾病有重要關聯。支持這種說法的醫學理論認為，當人體血液不流通時，將導致血管末端堵塞而形成摺痕。耳垂摺痕也被認為是血管的彈性蛋白量不足，反映出冠狀動脈的弱化。另外也有一派理論認為，耳朵是冠狀動脈噝械慕K點，耳垂折線即是冠狀動脈損害的徵兆。

 日本研究：對角線耳垂折線與DNA端粒受損有關

該篇報導也提到日本的研究，對角線耳垂折線（DELC）被認為是導致代謝綜合症的細胞端粒所形成的外顯樣貌，端粒是保護DNA鏈末端區域的物質，端粒受損將使身體的自愈及免疫能力下降。

他看「高血壓」卻被發現「90%冠狀動脈阻塞」

2014年的研究報告指出，曾有一名患者前往高血壓門鑰匆姡�痹抣現耳垂上有對角線摺痕，檢查後發現他的左主冠狀動脈有80阻塞，右冠狀動脈阻塞更高達90%，然而在此之前，他完全沒有心臟疾病的相關症狀。

         兩耳都有「對角線耳垂折線」最危險

目前對角線耳垂折線（DELC）被視為一種相關性指標，並且與地區文化有關，如果發現耳垂上有「單耳不完全」的折線屬於較不嚴重的等級，其次為單耳完全性摺痕，最嚴重的是兩耳完全性對角折線，患有心臟疾病的機率最高。

心臟疾病是致命的健康殺手之一，早期發現對於防治、就醫相當重要，因此，若觀察到有類似的耳垂異常徵兆，宜前往醫院由專科醫師進行全面檢查。

王毅見朝鮮外長後表示薩德入韓後，半島如發生衝突有美韓負責

【一虎一席談】美韓部署薩德 中國該不該強硬反制

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