| 关于铝的毒性 |
| 送交者: Justdoit 2003年03月07日01:47:57 于 [竞技沙龙] 发送悄悄话 |
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那天说油条时,谈到明矾的可能毒性。最近俺在准备一个重金属毒性及其预防操作的东东,找到点资料。献上有关信息如下,供有心人参考。 (http://www.luminet.net/~wenonah/hydro/al.htm#toxic) Aluminum has been exempted from tesitng for safety by the FDA under a convoluted logic wherein it is classified as GRAS. (Generally Regarded As Safe.) It has never been tested by the FDA on its safety and there are NO restrictions whatever on the amount or use of aluminum. There are over 2000 references in the National Library of Medicine on adverse effects of alumium. The following were extracted to provide a small sample of the range of toxicity of aluminum. Aluminum toxicity has been recognized in many settings where exposure is heavy or prolonged, where renal function is limited, or where apreviously accumulated bone burden is released in stress or illness. Toxicity may include: encephalopathy (stuttering, gait disturbance, myoclonic jerks, seizures, coma, abnormal EEG) osteomalacia or aplastic bone disease ( associated with painful spontaneous fractures, hypercalcemia, tumorous calcinosis ) proximal myopathy, increased risk of infection, increased left ventricular mass and decreased myocardial function microcytic anemia with very high levels, sudden death. Aluminum is ubiquitous in our environment; it is the third most pr????ent element in the earth's crust. The gastrointestinal tract is relatively impervious to aluminum, absorption normally being only about 2%. Aluminum is absorbed by a mechanism related to that for calcium. Gastric acidity and oral citrate favors absorption, and H2-blockers reduce absorption. As is true for several trace elements, transferrin is the primary protein binder and carrier for aluminum in the plasma, where 80% is protein bound and 20% is free or complexed to small molecules such as citrate. |
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