和充滿敵意和自以為是的態度。什麼“忠實擁躉”,“顯然也沒聽進去“今年之遺傳學已經不是去年的遺傳學”這話的意思”。
你的基因概念是標準答案嗎?只有你是權威,別人都不對?雖然你琢磨了10年,問題依然。我的理解,目前本質上只是不同的理解,沒有絕對對錯之分,人類基因組研究的官方網站,譯文的題目就是“How Many Genes Are in the Human Genome?”(見luye的跟貼),開頭和結尾說:
“Although the completion of the Human Genome Project was celebrated in April 2003 and sequencing of the human chromosomes is essentially "finished," the exact number of genes encoded by the genome is still unknown. October 2004 findings from The International Human Genome Sequencing Consortium, led in the United States by the National Human Genome Research Institute (NHGRI) and the Department of Energy (DOE), reduce the estimated number of human protein-coding genes from 35,000 to only 20,000-25,000, a surprisingly low number for our species (7). Consortium researchers have confirmed the existence of 19,599 protein-coding genes in the human genome and identified another 2,188 DNA segments that are predicted to be protein-coding genes.”
。。。。。
“Even with improved genome analysis, computation alone is simply not enough to generate an accurate gene number. Clearly, gene predictions will have to be verified by labor-intensive work in the laboratory before the scientific community can reach any real consensus .”
你誤解了我的基因概念,我說的表達調控不是單指調控轉錄,也包括翻譯調控及轉錄後、翻譯後調控等。我是這麼表述的:基因的概念包括編碼蛋白多肽和獨立功能性RNA的編碼核苷酸序列以及啟動子、增強子、Micro等附屬的表達調控性序列。在我的概念中,MicroRNA、反義RNA等算附屬調控序列,不算獨立基因。
當然,晚上仔細看了以後,發現我也誤讀了你的選擇性剪接,和選擇性轉錄的表述,你沒有混淆。向你表示抱歉。
除此之外,我堅持自己的看法,在我這幾天的陳述中,除了一個2450和DNA(應為核酸)兩個字誤外,沒有哪個概念有錯,搞學術的人,沒有你想象得那麼複雜,嘿嘿。