设万维读者为首页 广告服务 技术服务 联系我们 关于万维
简体 繁体 手机版
分类广告
版主:红树林
万维读者网 > 五 味 斋 > 跟帖
请夭夭先读点资料,弄懂腺病毒载体的疫苗作用机理后再来发言
送交者: 果子狸 2021月04月20日01:49:20 于 [五 味 斋] 发送悄悄话
回  答: 据果子狸说, 酸亦鲜 于 2021-04-20 01:11:57

这篇科普文章有图有真相,吃瓜群众都能看懂的。下面就是几个摘录的文字段落。

https://www.nytimes.com/interactive/2020/health/oxford-astrazeneca-covid-19-vaccine.html

The researchers added the gene for the coronavirus spike protein to another virus called an adenovirus. Adenoviruses are common viruses that typically cause colds or flu-like symptoms. The Oxford-AstraZeneca team used a modified version of a chimpanzee adenovirus, known as ChAdOx1. It can enter cells, but it can’t replicate inside them.

After the vaccine is injected into a person’s arm, the adenoviruses bump into cells and latch onto proteins on their surface. The cell engulfs the virus in a bubble and pulls it inside. Once inside, the adenovirus escapes from the bubble and travels to the nucleus, the chamber where the cell’s DNA is stored.

The adenovirus pushes its DNA into the nucleus. The adenovirus is engineered so it can’t make copies of itself, but the gene for the coronavirus spike protein can be read by the cell and copied into a molecule called messenger RNA, or mRNA.

The mRNA leaves the nucleus, and the cell’s molecules read its sequence and begin assembling spike proteins.

Some of the spike proteins produced by the cell form spikes that migrate to its surface and stick out their tips. The vaccinated cells also break up some of the proteins into fragments, which they present on their surface. These protruding spikes and spike protein fragments can then be recognized by the immune system.

The adenovirus also provokes the immune system by switching on the cell’s alarm systems. The cell sends out warning signals to activate immune cells nearby. By raising this alarm, the Oxford-AstraZeneca vaccine causes the immune system to react more strongly to the spike proteins.







0%(0)
      没有调查研究就没有发言权,这是个常识。  /无内容 - 果子狸 04/20/21 (57)
标  题 (必选项):
内  容 (选填项):
实用资讯
回国机票$360起 | 商务舱省$200 | 全球最佳航空公司出炉:海航获五星
海外华人福利!在线看陈建斌《三叉戟》热血归回 豪情筑梦 高清免费看 无地区限制