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請夭夭先讀點資料,弄懂腺病毒載體的疫苗作用機理後再來發言
送交者: 果子狸 2021月04月20日01:49:20 於 [五 味 齋] 發送悄悄話
回  答: 據果子狸說, 酸亦鮮 於 2021-04-20 01:11:57

這篇科普文章有圖有真相,吃瓜群眾都能看懂的。下面就是幾個摘錄的文字段落。

https://www.nytimes.com/interactive/2020/health/oxford-astrazeneca-covid-19-vaccine.html

The researchers added the gene for the coronavirus spike protein to another virus called an adenovirus. Adenoviruses are common viruses that typically cause colds or flu-like symptoms. The Oxford-AstraZeneca team used a modified version of a chimpanzee adenovirus, known as ChAdOx1. It can enter cells, but it can’t replicate inside them.

After the vaccine is injected into a person’s arm, the adenoviruses bump into cells and latch onto proteins on their surface. The cell engulfs the virus in a bubble and pulls it inside. Once inside, the adenovirus escapes from the bubble and travels to the nucleus, the chamber where the cell’s DNA is stored.

The adenovirus pushes its DNA into the nucleus. The adenovirus is engineered so it can’t make copies of itself, but the gene for the coronavirus spike protein can be read by the cell and copied into a molecule called messenger RNA, or mRNA.

The mRNA leaves the nucleus, and the cell’s molecules read its sequence and begin assembling spike proteins.

Some of the spike proteins produced by the cell form spikes that migrate to its surface and stick out their tips. The vaccinated cells also break up some of the proteins into fragments, which they present on their surface. These protruding spikes and spike protein fragments can then be recognized by the immune system.

The adenovirus also provokes the immune system by switching on the cell’s alarm systems. The cell sends out warning signals to activate immune cells nearby. By raising this alarm, the Oxford-AstraZeneca vaccine causes the immune system to react more strongly to the spike proteins.







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      沒有調查研究就沒有發言權,這是個常識。  /無內容 - 果子狸 04/20/21 (56)
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