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送交者: 慌兮兮 2007年04月03日10:46:16 於 [五 味 齋] 發送悄悄話

既然閻老師點了我的名,那我就再多說幾句關於乳房癌的話題。我不會因是哈佛的文章而退避。挾哈佛、挾洋文而令天下讀者的時代已相去甚遠了。

1) 首先,文章的題目就是講乳房尺寸以及和左、右手僻與乳房癌的關係。乳房的尺寸是間接地用cup size來衡量、統計。摘要中沒有一句提到乳房癌是由於戴胸罩而引起的。怎麼到了閻老師的文章里就變成是戴胸罩會引起乳房癌?至於乳房尺寸和乳房癌的關聯,我就不用多提了。閻老師一天要讀十幾小時的書,我相信這致癌機理閻老師一定能琢磨出來。

2) 文章只提及以上兩因素可能和乳房癌有關(suggestive),並沒有肯定。P value只有一個是0.026,有意義的統計值,別的都沒有達標。怎麼到了閻老師的文章里就變成是有確鑿的科學證據的?是否應該讓男同學戴上胸罩試試,看乳房癌的發病率會不會有所提高?

3) 昨天給出的戴胸罩引發乳房癌的機理是因淋巴管被胸罩壓迫、堵塞。那真是無稽之談。“醫生”和“南泥灣”引文中指出這原來是兩位開夫妻老婆店的江湖術士般的人類學家提出的。毫無科學根據,是憑想象得出的結論。

4) 一個人的知識是非常有限的。不要說一天讀十幾小時的書、文章,就是一天讀24小時的書和文章也不可能把所有的東西都看過來,更不要說理解、讀明白了。所以讀書、看文章時個人的思考、分析和判斷比實際能讀多少書、看多少文章更重要。

下文是閻老師引用的哈佛文章摘要的原文,同學們自己可以判斷真偽:

Eur J Cancer. 1991;27(2):131-5. Links
Breast size, handedness and breast cancer risk.Hsieh CC, Trichopoulos D.
Department of Epidemology, Harvard School of Public Health, Boston, Massachusetts 02115.
Bra cup size and handedness were studied as possible risk factors for breast cancer. Data for 3918 cases and 11,712 controls from 7 centres were used to examine the association of handedness with laterality of breast cancer; data for 2325 cases and 7008 controls from 4 centres were used to assess the relation of bra cup size to breast cancer risk. There was a suggestive (P about 0.10) association of handedness with breast cancer laterality: odds ratio of a left-handed (or ambidextrous) woman having a left-sided cancer 1.22 (95% CI 0.96-1.56). Handedness may affect the lateral occurrence of breast cancer, although this tumour is in general more common in the left breast, possibly because this breast is usually slightly larger. Premenopausal women who do not wear bras had half the risk of breast cancer compared with bra users (P about 0.09), possibly because they are thinner and likely to have smaller breasts. Among bra users, larger cup size was associated with an increased risk of breast cancer (P about 0.026), although the association was found only among postmenopausal women and was accounted for, in part, by obesity. These data suggest that bra cup size (and conceivably mammary gland


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